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Summer Undergraduate Research Assistant

Your Role

Job TitleSummer Undergraduate Research Assistant
Duties and ResponsibilitiesThe student will take the appropriate biosafety training through UM Learn and will learn experimental techniques for performing cell culture, protein immunoprecipitation and blotting, RNA interference and quantitative PCR. Once sufficiently trained, the student will design and carry out their own experiments with assistance from a lab technician. The student will be guided in appropriate data analysis practices and will be encouraged to present their research at the Fall 2021 undergraduate research poster competition.
Skills and Benefits to be Gained from this PositionThe student will learn: -Cell culture methods and techniques -Protein immunoprecipitation and western blotting -RNA interference and quantitative PCR -Science communication skills These will benefit the student by: -Preparation to undertake further research studies or work (e.g. graduate school) -Giving opportunities to improve science communication skills
Involvement of Animals, Humans and/or HazardsHazardsMouse cell line work

How to Apply

DeadlineJanuary 05, 2021
University LevelUndergraduate
Application MethodPlease contact Dr. Thompson by email
Required Application Materials
  • A statement indicating the school, program and year that you are currently enrolled in.

The Project

Project TitleIdentifying novel transcriptional regulators of beta cell senescence in Type 1 Diabetes
Project DescriptionA summer undergraduate research position is available in the laboratory of Dr. Peter Thompson, in the Children's Hospital Research Institute of Manitoba (CHRIM) at the Bannatyne campus. The Thompson lab investigates the molecular mechanisms of Type 1 Diabetes (T1D), a metabolic disease characterized by insulin deficiency due to autoimmune destruction of pancreatic beta cells. Learn more at the lab website: https://www.thompsonlab.ca Previous work in the lab has demonstrated that some beta cells acquire a growth arrested, inflammatory state called senescence which drives the onset of T1D. How this state is regulated remains unclear. In this project, the student will address this research question using a mouse beta cell line model to identify new transcriptional regulators of senescence in beta cells. They will learn basic cell culture methods, biochemistry (protein immunoprecipitation & western blotting) and genetic tools to explore gene function and expression (RNA interference, quantitative PCR). This position is ideally suited for 2nd or 3rd year student with a background in molecular or cell biology, genetics or biochemistry. The student will apply with Dr. Thompson for an Undergraduate Research Award (URA) for this position.
Researcher/SupervisorDr. Peter Thompson
FacultyRady Faculty of Health Sciences
Department/SchoolPhysiology & Pathophysiology

Job Terms

Number of Jobs1
Job DatesMay 03, 2021 to August 27, 2021
Salary$7,000.00/summer term
Other InformationPosition contingent on summer undergraduate research award (URA) funding. See: http://umanitoba.ca/research/opportunities-support/undergraduate-research-awards

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